Juvenile nasopharyngeal angiofibromas occur almost exclusively in males and usually in adolescence 15 years. The tumour is sessile or polypoid and is histologically benign, but has a tendency to recur and is locally destructive, causing pressure necrosis of adjacent soft tissue and bone. Juvenile nasopharyngeal angiofibroma is tumour almost exclusively seen in adolescent males, constituting less than 1% of all neoplasms in. Juvenile nasopharyngeal angiofibroma jna is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. Juvenile nasopharyngeal angiofibroma jna is a histologically. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. Typical signs are nasal and eustachian tube obstruction, adenoidal speech, and dysphagia. In this video, we are going to see about juvenile nasopharyngeal angiofibroma. Given its vascularity, prominent flow voids are seen on mri leading to a salt and pepper appearance. Pdf this is a retrospective study that aimed to examine the outcomes of patients presenting with juvenile nasopharyngeal angiofibroma jna at a. We aimed to report the characteristic magnetic resonance imaging mri findings and the spread patterns of jna. Review article nasopharyngeal angiofibroma ashutosh hota. Jna berasal dari posterolateral nasofaring di daerah fossa pterygopallatine. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that exhibits a predictable spreading pattern.
Nasopharyngeal angiofibroma an overview sciencedirect. Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male predominance. Jan 11, 2011 juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Juvenile nasopharyngeal angiofibroma radiology case.
Health, general endoscopic surgery complications and side effects patient outcomes endoscopy nasopharyngeal cancer care and treatment diagnosis risk factors. Shaheen in 1930 reported the first female patient with juvenile nasopharyngeal. Hmm, seems to be two editions of this book with separate book pages. A male, 21 years of age, without relevant history, presented with left exophthalmos and diplopia in extreme gaze positions with 2 weeks evolution, without clinic of epistaxis or nasal obstruction. Juvenile nasopharyngeal angiofibroma jna is a histologically benign vascular tumor that arises in boys between the ages of 12 and 15 years, with only rare cases reported in patients younger than 10 or older than 25. Jul 15, 2015 juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Juvenile nasopharyngeal angiofibroma jna is an uncommon, benign tumor of the nose that is generally seen in boys. Javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Angiofibroma nasofaring belia anb merupakan tumor jinak secara. Juvenile nasopharyngeal angiofibroma merupakan tumor jinak kepala leher langka pada remaja lakilaki namun mempunyai risiko invasi yang tinggi karena. Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. Juvenile nasopharyngeal angiofibromas jna are a rare benign, but locally aggressive, vascular tumor. Juvenile nasopharyngeal angiofibroma with orbital extension.
Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. Pdf juvenile nasopharyngeal angiofibroma researchgate. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. The tumor usually arises in puberty and is more common in boys than in girls. Their use is purely for academic and teaching purposes.
Review article nasopharyngeal angiofibroma ashutosh hota s. As the tumor is largely spaceoccupying and highly vascular, patients typically. Angiofibroma septum salah satu tumor angiofibroma ekstranasofaring yang sangat jarang terjadi. Magnetic resonance imaging findings ayse gul alimli, murat ucar, cigdem oztunali, koray akkan, oznur boyunaga, cagr. Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. May 16, 2018 nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Axial ct, soft tissue and bone windows, at the level of the maxillary sinus show characteristic features of juvenile nasopharyngeal angiofibroma. Wahidin sudirohusodo makassar dan rs pendidikan unhas. We report the case of a 17yearold male who presented in 1995 with a mass filling the left posterior nasal cavity.
Angiofibroma nasofaring juvenil perhimpunan onkologi radiasi. The juvenile nasopharyngeal angiofibroma is a benign neoplasm of the posterior. Abstrak angiofibroma nasofaring adalah tumor jinak nasofaring yang secara histopatologis merupakan tumor jinak, tetapi secara klinis bersifat destruktif. A juvenile nasopharyngeal angiofibroma jna is a noncancerous tumor made up of blood vessels that grow at the posterior aspect of the nose. Juvenile nasopharyngeal angiofibroma iowa head and neck. Jnas occur almost exclusively in the nasopharynx of adolescent. Juvenile nasopharyngeal angiofibroma boston childrens hospital.
Juvenile nasopharyngeal angiofibroma otorrinos2dos blog. These tumors are benign, however they are locally invasive. Tumor ini memiliki histopatologi yang sama dengan angiofibroma nasofaring. The tumor is locally aggressive and can invade into surrounding structures and cause significant complications. Juvenile nasopharyngeal angiofibroma jna represents.
Jnas originate from the posterior choanal tissues and rapidly extend into the surrounding regions, including the nasopharynx, the orbits, and even the intracranial cavity. The present article is a retrospective study of surgically treated patients of juvenile nasopharyngeal angiofibroma over a period of 5 years. Juvenile nasopharyngeal angiofibroma jna is a rare, benign, but locally aggressive tumor occurring almost exclusively in adolescent males. Doc lapsus angiofibroma nasofaring anggy novitasari. Embolisasi pva partikel foamprasyarat preoperatif pada. They often grow quickly during puberty, then slow down or stop growing entirely after adolescence. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns. Tumor ini sering terjadi pada lakilaki prepubertas dan remaja, jarang ditemukan pada pasien. May 16, 2018 despite tumor reduction with hormones, this approach is not routinely used. Pdf juvenile nasopharyngeal angiofibroma in a tertiary centre. Juvenile nasopharyngeal angiofibroma jna javiers story. In the general population, jna occurs at an incidence of roughly 1. Juvenile nasopharyngeal angiofibroma knowledge for medical.
Angiofibroma nasofaring juvenile free download as pdf file. Nasopharyngeal angiofibroma symptoms aurora health care. Juvenile nasopharyngeal angiofibroma is a benign but locally invasive tumor accounting for about 0. The pictures used in this presentation have been obtained from a number of sources. Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Juvenile nasopharyngeal angiofibromas are a rare benign, but locally aggressive, vascular tumors that occur almost exclusively in young men on imaging, they present as a vividly enhancing softtissue masses centered on the sphenopalatine foramen. Sep 01, 2008 juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that predominantly occurs in adolescent males, the average age of occurence being 15. Angiofibroma nasofaring belia pdf juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The tumor contains many blood vessels and spreads within the area in which it. Although rare cases have been reported in females, the tumor has such a strong male. It most commonly affects adolescent males because it is a hormonesensitive tumor.
Juvenile nasopharyngeal angiofibroma for medical students. It is the most common benign tumor of the nasopharnyx but only accounts for less than 0. Juvenile nasopharyngeal angiofibroma jna jnas are wellvascularized benign lesions typically occurring in adolescent males. Nasopharyngeal angiofibroma definition of nasopharyngeal. The juvenile nasopharyngeal angiofibroma has a characteristic growth in all directions from its origin. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. Insiden dari angiofibroma tinggi dibeberapa bagian dari belahan dunia, seperti pada timur tengah dan amerika. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for. Nasopharyngeal angiofibroma an overview sciencedirect topics. Juvenile nasopharyngeal angiofibroma radiology reference. Juvenile nasopharyngeal angiofibroma, surgical approach, recurrence, residual disease introduction juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor occurring mainly in adolescent boys. Introduction uncommon, benign and extremely vascular tumour up to 0. Transnasal endoscopic resection of juvenile nasopharyngeal angiofibroma without preoperative embolization.
In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. Jna biasanya selalu meluas melalui foramen sphenopallatine, meliputi fossa pterygopallatine dan cavum nasal posterior. Juvenile nasopharyngeal angiofibroma boston childrens. The incidence of juvenile nasopharyngeal angiofibroma is 0. Visual acuity was 2020 in both eyes and intraocular pressure iop 24 mmhg in left eye le without limitations in ocular movement. Pdf imaging in the diagnosis of juvenile nasopharyngeal.
Mar 07, 2020 it most commonly affects adolescent males and may grow into fissures of the. Juvenile nasopharyngeal angiofibroma jna is a benign vascular tumor that appears in the nasal cavity. Laporan kasus serial dari lima pasien muhammad yunus amran1,2, ashari bahar1,3 1staf dosen dan klinikal pada departemen neurologi, fakultas kedokteran universitas hasanuddin, rsup dr. Martin, ehrlich dan abels 1948 melaporkan ratarata setiap tahunnya dari satu atau dua pasien untuk 2000 pasien yang diobati pada head and neck service of the memorial hospital, new york. Ppt juvenile nasopharyngeal angiofibroma powerpoint. This is a concise presentation for medical students especially from india. Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. Juvenile nasopharyngeal angiofibroma jna is a rare histologically benign tumor, highly vascularized, with usually aggressive behavior, and can extend from the nasal cavity to neighboring structures. Bedah sinonasal endoskopik angiofibroma nasofaring belia. Diagnosis and treatment of juvenile nasopharyngeal. The juvenile nasopharyngeal angiofibroma is a benign neoplasm of the posterior nasopharynx it occurs almost exclusively in adolescent males, with an average age at diagnosis of 15 years old. Radiologists prior knowledge on the tumors characteristics aids in establishing a diagnosis. Infact hippocrates goes on to describe a polyp in the nose which weeped blood.
Common practice is to excise the tumor with open or endoscopic surgery. Juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Juvenile nasopharyngeal angiofibroma has been documented since the time of hippocrates 4 bc. Patients usually present with nasal obstruction and epistaxis.
Although it is nonmalignant not cancerous, it can expand quickly and extensively. Juvenile nasopharyngeal angiofibroma a free powerpoint ppt presentation displayed as a flash slide show on id. Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma with orbital extension angiofibroma nasofaringeo juvenil con extension orbitaria. There is an enhancing mass expanding and extending into the posterior nasal air space with erosion of the base of the right pterygoid plate and lateral extension to the infratemporal fossa. These features are compatible with juvenile angiofibroma, a benign but locally invasive tumor. However, the extensions of the tumor seem to be independent, each one with distinct behavior. Juvenile angiofibroma rads see also with virtual slide. Jan 08, 2018 javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Jna can spread into a variety of compartments in the head including the sinuses, the orbit where the eye is located, and the brain which can make. It most commonly affects adolescent males and may grow into fissures of the. Despite tumor reduction with hormones, this approach is not routinely used. It is a rare, benign, vascular neoplasm that accounts for less than 0. Sep 17, 2010 the management of juvenile nasopharyngeal angiofibroma jna has changed during the last decades but it still continues to be a challenge for the multidisciplinary head and neck surgical team.
Diagnosis dan penatalaksanaan angiofibroma septum nasi jurnal. The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. Dec 21, 2015 axial ct, soft tissue and bone windows, at the level of the maxillary sinus show characteristic features of juvenile nasopharyngeal angiofibroma. Schuon et al reported on the immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma knowledge for. The aim of this retrospective study was to compare clinical and radiological findings and discuss optimal surgical approach in patients with juvenile nasopharyngeal angiofibroma jna. Management of juvenile nasopharyngeal angiofibroma. Some reports suggest juvenile nasopharyngeal angiofibroma is more common in the indian subcontinent than in the west. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation.
Juvenile angiofibroma is a rare benign lesion originating from the. Juvenile nasopharyngeal angiofibroma arises in the confluence of the posterolateral nasal wall and the lateral nasopharynx and occurs almost exclusively in males during adolescence. However, this case is not typical as it doesnt invade the nasal fossae. Transnasal endoscopic resection of juvenile nasopharyngeal. Juvenile nasopharyngeal angiofibroma j na adalah operasi. This is a concise presentation for medical students especially from. They concluded that juvenile angiofibroma jna growth and vascularization are driven by factors released from stromal fibroblasts. Tumor juga lebih sering meluas ke arah sinus sphenoid dan agak jarang ke arah sinus. The changing surgical management of juvenile nasopharyngeal. The management of juvenile nasopharyngeal angiofibroma jna has changed during the last decades but it still continues to be a challenge for the. Juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor of the nasopharynx, comprising only 0. Juvenile nasopharyngeal angiofibroma evaluation and workup return to. Please choose whether or not you want other users to be able to see on your profile that deuss library is a favorite of yours. Juvenile nasopharyngeal angiofibroma electronic journal of.
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