Common practice is to excise the tumor with open or endoscopic surgery. Nasopharyngeal angiofibroma symptoms aurora health care. Juvenile nasopharyngeal angiofibroma iowa head and neck. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. Javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Juvenile nasopharyngeal angiofibromas occur almost exclusively in males and usually in adolescence 15 years. The pictures used in this presentation have been obtained from a number of sources. Mar 07, 2020 it most commonly affects adolescent males and may grow into fissures of the. It is the most common benign tumor of the nasopharnyx but only accounts for less than 0. Abstrak angiofibroma nasofaring adalah tumor jinak nasofaring yang secara histopatologis merupakan tumor jinak, tetapi secara klinis bersifat destruktif. Review article nasopharyngeal angiofibroma ashutosh hota s. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns.
Juvenile nasopharyngeal angiofibroma electronic journal of. Juvenile nasopharyngeal angiofibroma jna is a benign vascular tumor that appears in the nasal cavity. Juvenile nasopharyngeal angiofibroma boston childrens hospital. The changing surgical management of juvenile nasopharyngeal. In this video, we are going to see about juvenile nasopharyngeal angiofibroma. Magnetic resonance imaging findings ayse gul alimli, murat ucar, cigdem oztunali, koray akkan, oznur boyunaga, cagr. Nasopharyngeal angiofibroma definition of nasopharyngeal. Juvenile angiofibroma rads see also with virtual slide. These tumors are benign, however they are locally invasive. Juvenile nasopharyngeal angiofibroma is tumour almost exclusively seen in adolescent males, constituting less than 1% of all neoplasms in. Doc lapsus angiofibroma nasofaring anggy novitasari.
The management of juvenile nasopharyngeal angiofibroma jna has changed during the last decades but it still continues to be a challenge for the. It most commonly affects adolescent males and may grow into fissures of the. Sep 01, 2008 juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. These features are compatible with juvenile angiofibroma, a benign but locally invasive tumor. Juvenile nasopharyngeal angiofibroma jna is a rare benign tumor arising predominantly in the nasopharynx of adolescent males.
Juvenile angiofibroma is a rare benign lesion originating from the. Juvenile nasopharyngeal angiofibroma knowledge for. Juvenile nasopharyngeal angiofibroma jna represents. Despite tumor reduction with hormones, this approach is not routinely used. Tumor ini sering terjadi pada lakilaki prepubertas dan remaja, jarang ditemukan pada pasien. A juvenile nasopharyngeal angiofibroma jna is a noncancerous tumor made up of blood vessels that grow at the posterior aspect of the nose. Juvenile nasopharyngeal angiofibroma for medical students. Please choose whether or not you want other users to be able to see on your profile that deuss library is a favorite of yours. The present article is a retrospective study of surgically treated patients of juvenile nasopharyngeal angiofibroma over a period of 5 years. Angiofibroma septum salah satu tumor angiofibroma ekstranasofaring yang sangat jarang terjadi.
Diagnosis dan penatalaksanaan angiofibroma septum nasi jurnal. Given its vascularity, prominent flow voids are seen on mri leading to a salt and pepper appearance. Insiden dari angiofibroma tinggi dibeberapa bagian dari belahan dunia, seperti pada timur tengah dan amerika. This is a concise presentation for medical students especially from india. A male, 21 years of age, without relevant history, presented with left exophthalmos and diplopia in extreme gaze positions with 2 weeks evolution, without clinic of epistaxis or nasal obstruction. The tumor is locally aggressive and can invade into surrounding structures and cause significant complications. Juvenile nasopharyngeal angiofibroma jna is a rare histologically benign tumor, highly vascularized, with usually aggressive behavior, and can extend from the nasal cavity to neighboring structures. Transnasal endoscopic resection of juvenile nasopharyngeal. Jna biasanya selalu meluas melalui foramen sphenopallatine, meliputi fossa pterygopallatine dan cavum nasal posterior. Juvenile nasopharyngeal angiofibroma with orbital extension angiofibroma nasofaringeo juvenil con extension orbitaria.
Schuon et al reported on the immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma. Jan 08, 2018 javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. Juvenile nasopharyngeal angiofibromas are a rare benign, but locally aggressive, vascular tumors that occur almost exclusively in young men on imaging, they present as a vividly enhancing softtissue masses centered on the sphenopalatine foramen. Juvenile nasopharyngeal angiofibroma radiology case. Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. Radiologists prior knowledge on the tumors characteristics aids in establishing a diagnosis. However, the extensions of the tumor seem to be independent, each one with distinct behavior. The juvenile nasopharyngeal angiofibroma has a characteristic growth in all directions from its origin. Angiofibroma nasofaring juvenile free download as pdf file. Pdf this is a retrospective study that aimed to examine the outcomes of patients presenting with juvenile nasopharyngeal angiofibroma jna at a. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that predominantly occurs in adolescent males, the average age of occurence being 15.
Although rare cases have been reported in females, the tumor has such a strong male. Nasopharyngeal angiofibroma an overview sciencedirect topics. Management of juvenile nasopharyngeal angiofibroma. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. Wahidin sudirohusodo makassar dan rs pendidikan unhas. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade. Tumor juga lebih sering meluas ke arah sinus sphenoid dan agak jarang ke arah sinus. They concluded that juvenile angiofibroma jna growth and vascularization are driven by factors released from stromal fibroblasts. Angiofibroma nasofaring belia anb merupakan tumor jinak secara. Their use is purely for academic and teaching purposes. Martin, ehrlich dan abels 1948 melaporkan ratarata setiap tahunnya dari satu atau dua pasien untuk 2000 pasien yang diobati pada head and neck service of the memorial hospital, new york. Juvenile nasopharyngeal angiofibroma merupakan tumor jinak kepala leher langka pada remaja lakilaki namun mempunyai risiko invasi yang tinggi karena.
However, this case is not typical as it doesnt invade the nasal fossae. Bedah sinonasal endoskopik angiofibroma nasofaring belia. Juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor of the nasopharynx, comprising only 0. The juvenile nasopharyngeal angiofibroma is a benign neoplasm of the posterior nasopharynx it occurs almost exclusively in adolescent males, with an average age at diagnosis of 15 years old. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for. Angiofibroma nasofaring juvenil perhimpunan onkologi radiasi. The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. Juvenile nasopharyngeal angiofibromas jna are a rare benign, but locally aggressive, vascular tumor.
Laporan kasus serial dari lima pasien muhammad yunus amran1,2, ashari bahar1,3 1staf dosen dan klinikal pada departemen neurologi, fakultas kedokteran universitas hasanuddin, rsup dr. Juvenile nasopharyngeal angiofibroma j na adalah operasi. Diagnosis and treatment of juvenile nasopharyngeal. We aimed to report the characteristic magnetic resonance imaging mri findings and the spread patterns of jna.
Juvenile nasopharyngeal angiofibroma boston childrens. The aim of this retrospective study was to compare clinical and radiological findings and discuss optimal surgical approach in patients with juvenile nasopharyngeal angiofibroma jna. Sep 17, 2010 the management of juvenile nasopharyngeal angiofibroma jna has changed during the last decades but it still continues to be a challenge for the multidisciplinary head and neck surgical team. They often grow quickly during puberty, then slow down or stop growing entirely after adolescence. The tumor usually arises in puberty and is more common in boys than in girls.
Juvenile nasopharyngeal angiofibroma jna jnas are wellvascularized benign lesions typically occurring in adolescent males. May 16, 2018 despite tumor reduction with hormones, this approach is not routinely used. Dec 21, 2015 axial ct, soft tissue and bone windows, at the level of the maxillary sinus show characteristic features of juvenile nasopharyngeal angiofibroma. Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. Nasopharyngeal angiofibroma an overview sciencedirect. Jnas originate from the posterior choanal tissues and rapidly extend into the surrounding regions, including the nasopharynx, the orbits, and even the intracranial cavity. Introduction uncommon, benign and extremely vascular tumour up to 0. Juvenile nasopharyngeal angiofibroma is a benign but locally invasive tumor accounting for about 0. We report the case of a 17yearold male who presented in 1995 with a mass filling the left posterior nasal cavity. Juvenile nasopharyngeal angiofibroma jna is an uncommon, benign tumor of the nose that is generally seen in boys.
The tumour is sessile or polypoid and is histologically benign, but has a tendency to recur and is locally destructive, causing pressure necrosis of adjacent soft tissue and bone. Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. Pdf imaging in the diagnosis of juvenile nasopharyngeal. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that exhibits a predictable spreading pattern. Tumor ini memiliki histopatologi yang sama dengan angiofibroma nasofaring. Juvenile nasopharyngeal angiofibroma otorrinos2dos blog. Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Although it is nonmalignant not cancerous, it can expand quickly and extensively. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma jna is a histologically. Juvenile nasopharyngeal angiofibroma knowledge for medical. Health, general endoscopic surgery complications and side effects patient outcomes endoscopy nasopharyngeal cancer care and treatment diagnosis risk factors. Axial ct, soft tissue and bone windows, at the level of the maxillary sinus show characteristic features of juvenile nasopharyngeal angiofibroma.
Shaheen in 1930 reported the first female patient with juvenile nasopharyngeal. Jna can spread into a variety of compartments in the head including the sinuses, the orbit where the eye is located, and the brain which can make. Jul 15, 2015 juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Review article nasopharyngeal angiofibroma ashutosh hota. Hmm, seems to be two editions of this book with separate book pages.
Pdf juvenile nasopharyngeal angiofibroma researchgate. Angiofibroma nasofaring belia pdf juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. Juvenile nasopharyngeal angiofibroma, surgical approach, recurrence, residual disease introduction juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor occurring mainly in adolescent boys. In the general population, jna occurs at an incidence of roughly 1. Juvenile nasopharyngeal angiofibroma jna is a rare, benign, but locally aggressive tumor occurring almost exclusively in adolescent males. The incidence of juvenile nasopharyngeal angiofibroma is 0. Juvenile nasopharyngeal angiofibroma jna is a histologically benign vascular tumor that arises in boys between the ages of 12 and 15 years, with only rare cases reported in patients younger than 10 or older than 25. Jan 11, 2011 juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Juvenile nasopharyngeal angiofibroma jna javiers story.
The juvenile nasopharyngeal angiofibroma is a benign neoplasm of the posterior. Juvenile nasopharyngeal angiofibroma radiology reference. The tumor contains many blood vessels and spreads within the area in which it. Juvenile nasopharyngeal angiofibroma has been documented since the time of hippocrates 4 bc. Typical signs are nasal and eustachian tube obstruction, adenoidal speech, and dysphagia. Patients usually present with nasal obstruction and epistaxis. Ppt juvenile nasopharyngeal angiofibroma powerpoint. Visual acuity was 2020 in both eyes and intraocular pressure iop 24 mmhg in left eye le without limitations in ocular movement. Juvenile nasopharyngeal angiofibroma with orbital extension. Pdf juvenile nasopharyngeal angiofibroma in a tertiary centre. Infact hippocrates goes on to describe a polyp in the nose which weeped blood.
May 16, 2018 nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. This is a concise presentation for medical students especially from. Juvenile nasopharyngeal angiofibroma a free powerpoint ppt presentation displayed as a flash slide show on id. Embolisasi pva partikel foamprasyarat preoperatif pada. Some reports suggest juvenile nasopharyngeal angiofibroma is more common in the indian subcontinent than in the west. Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male predominance. Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. It most commonly affects adolescent males because it is a hormonesensitive tumor.
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